Brain Science Institute
Biomedical Research
      Institute
Institute for Multi-disciplinary
      Convergence of Materials
Green City Technology
      Institute
Future Convergence
      Research Division
National Agenda Research
      Division
Research Plannig &
      Coordination Division
INTRODUCTION

Since human history began, it has been the greatest interest for the human race to live a healthy, prosperous life with no disease. In spite of the cutting-edge medical techniques, we have higher chances to suffer from new and incurable diseases due to the highly-ordered, advanced social complexity and growing average lifespan. However, the recent remarkable development of our life science technology has led us to understand mechanisms of human diseases down to the molecular level, and by doing so, we are now able to come up with new therapeutical targets and approach toward the cure. Biomolecules Function Research Center contributes to the treatment/prevention of disease and the improvement of human health/well-being by understanding the overall interactions between living organisms and chemical substances and applying it to the personalized medicine and to accomplish this mission we have two different approaches. One is to identify biological functions and interactions between molecules through OMICs technology. The Center has conducted a wide range of researches based on the analytical techniques to trace bio/environmental materials using ultra precision analytical equipments : metabolomics, peptidomics, pharmacology, toxicology, pharmacokinetics, risk assessment on chemical substances, and systems biology. The other one is to study disease mechanisms at the molecular level, to suggest effective targets, and ultimately to develop bioactive molecules as novel drug candidates. The discovery and validation of novel protein targets by chemical biology is also under construction to accomplish this goal.

Acting Head : Dr. Jung, Byung Hwa
+82-2-958-5062
+82-2-958-5059
jbhluck@kist.re.kr
Major research field
Metabolomics
Biomolecular analysis using CE and MS
Study of signal trasduction
ADME
Pharmacological and toxicological analysis of drug candidates
Bioinformatics, Protein Structure Modeling
Diagnostic Probe Library Synthesis, Fluorescent Probe Development
Epigenetic Profiling Method Development
Bioactive Molecules Screening
Knowledge-Based Drug Design and Synthesis (Medicinal Chemistry)
Chemical biology
Research Teams
Metabolomic Profiling Laboratory(www.metabolomicslab.org)
Chemical Biology & Informatics Laboratory(http://chembiol.kist.re.kr)
Biochemistry Laboratory(http://biochemistry.kist.re.kr)
Pharmacology and Toxicology Laboratory
Medicinal Chemistry Laboratory
Chemical biology Laboratory