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Doping Control Center
Advanced Analysis Center
 
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INTRODUCTION

The Doping Control Center was originally founded in Korea Institute of Science and Technology in 1984 to conduct doping tests at the ¡®86 Asian Games and the ¡®88 Olympic Games in Seoul. As an official test laboratory accredited by International Olympic Committee (IOC), the center successfully performed the functions at the games. Since establishment of the World Anti-Doping Agency (WADA) in 1999, the Center as one of WADA-accredited laboratories has continued to contribute to the prevention of drug abuse in sports through research into new analytical methods for detecting newly added prohibited substances. Recently, new doping tools such as designer steroids/stimulants, peptide hormones, blood transfusion and gene doping have been introduced to avoid detection by conventional test methods. In order to respond to these new challenges, the Center has strengthened international and local cooperative research and newly upgraded its doping control test/center system, which will significantly expand detection capabilities involving variable and unexpected situations.

Head : Dr. Kwon, Oseung
02)958-5184
02)958-6677
oskwon@kist.re.kr
Major Field for Doping Analysis and Research
Improvement of detection method and development of a new analytical method for banned drugs

Study on steroid profiles of athletes

- Detection of pro-hormone and designer steroids and the criteria for intake of endogenous steroids using C-IR/MS
- Ethnic differences in steroid profiles

Blood doping

Detection of peptide hormones

- Development of analytical method of the peptides in urine and plasma by LC-MS/MS
- Monitoring exogenous EPO, hCG, hGH in urine or blood
Gene doping method
Main Achievements
RE-accreditation by World Anti-Doping Agency

Doping test for 2002 Korea-Japan Worldcup and 2002 Pusan Asian Games.

Doping test for 2005 Incheon Asian Athletics Championship

Doping test for 2011 Daegu IAAF World Athletic Championships

Development of the method to determine the origin of endogenous steroids
Development of simultaneous analytical methods to detect 220 prohibited substances.
Instruments
GC/MSD (5973, 5975): Stimulants, Narcotics, Steroids

Quadrupole LC-MS/MS system: Hormone antagonist and Modulators, ¥â2-Antagonists, Diurectics, Glucocorticoids

High-Resolution GC/MS system: Confirmation of Steroids

Combustion-Isotope Ratio MS: Confirmation of endogenous steroids

LTQ-Orbitrap MS: Protein/peptide, Steroids
Flow Cytometer: Blood transfusion
Elecsys 2010/Access 2 Immunoassay System: hCG
Iso-electric Focusing Gel System: EPO and EPO analogues
Automatic Luminometer: hGH
Automated Hematology & Reticulocyte Analyzer (Sysmex): Blood parameters